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Rho-Kinase in Development and Heart Failure: Insights From Genetic Models

✍ Scribed by Jianjian Shi; Lumin Zhang; Lei Wei

Publisher
Springer
Year
2011
Tongue
English
Weight
257 KB
Volume
32
Category
Article
ISSN
0172-0643

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## Abstract The Rho‐kinase (ROCK) plays an important role in the pathogenesis of heart injury. Recent cellular and molecular biology studies indicated a pivotal role of the RhoA/ROCK cascade in many aspects of cardiovascular function such as heart failure, cardiac hypertrophy, and ventricular remod