Catabolism of Branched-Chain Amino Acids in Heart Failure: Insights from Genetic Models
β Scribed by Haipeng Sun; Gang Lu; Shuxun Ren; Jaunian Chen; Yibin Wang
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 581 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0172-0643
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π SIMILAR VOLUMES
Branched-chain amino acids (BCAA) are known to improve hepatic encephalopathy as well as protein malnutrition in cirrhosis. However, such effects in acute hepatic failure (AHF) remain to be elucidated. The current study was conducted to investigate whether BCAA improves protein metabolism in AHF. AH
## Abstract **Scope:** We hypothesized that chronic supplementation with branched chain amino acids (BCAAs) affects neurobehavioral development in vulnerable gene backgrounds. **Methods and results:** A murine model of amyotrophic lateral sclerosis (ALS), G93A mice bearing the mutated human supero