Rheumatoid synovial cell morphologic cha
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Daniel G. Baker; Jean-Michel Dayer; Merrilee Roelke; H. Ralph Schumacher; Stephe
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Article
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1983
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John Wiley and Sons
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English
β 713 KB
Adherent rheumatoid synovial cells in culture produce large amounts of prostaglandin E2 (PGE2) and collagenase. When exposed to a monocyte-derived factor, such cells exhibit marked increases in PGE2 and collagenase production. In addition, cellular morphology becomes more stellate. In the presence o