rhBMP-2 Modulation of Gene Expression in Infected Segmental Bone Defects
β Scribed by Katherine E. Brick; Xinqian Chen; Jamie Lohr; Andrew H. Schmidt; Louis S. Kidder; William D. Lew
- Book ID
- 107562980
- Publisher
- Springer-Verlag
- Year
- 2008
- Tongue
- English
- Weight
- 315 KB
- Volume
- 467
- Category
- Article
- ISSN
- 0009-921X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
A β€-tricalcium phosphate-monocalcium phosphate monohydrate (β€-TCP-MCPM) cement was evaluated as an effective carrier of recombinant human bone morphogenetic protein-2 (rhBMP-2) in rat femoral critical-size defects. Hard cement cylinders (4 Γ 5 mm) impregnated with two different doses of rhBMP-2 (1.2
## Abstract Carriers for bone morphogenetic proteinβ2 (BMPβ2) used in clinical practice still suffer from limitations such as insufficient protein retention. In addition, there is a clinical need for injectable carriers. The main objective of this study was to assess bone forming ability of rhBMPβ2
## Abstract Recombinant human bone morphogenetic proteinβ (rhBMPβ) can be used to enhance the repair of congenital or acquired bone pathologies when formulated in the appropriate carrier. Poly [D, Lβ(lactideβcoβglycolide)] (PLGA) has been shown to be an effective carrier of rhBMPβ. We investigated