RGD peptides inhibit osseointegration of hydroxyapatite implants
β Scribed by K.M. Hennessy; S.L. Bellis
- Book ID
- 116729361
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 65 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0945-053X
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Hydroxyapatite (HA) is a widely-used biomaterial for bone repair due to its high degree of osteoconductivity. However, strategies for improving HA performance by functionalizing surfaces with bioactive factors are limited. In this study, we explored the use of a HA-binding domain (heptaglutamate, "E
## Abstract For the last 15 years, orthopedic implants have been coated with hydroxyapatite (HA) to improve implant fixation. The osteoconductive effect of HA coatings has been demonstrated in experimental and clinical studies. However, there are ongoing developments to improve the quality of HA co