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RGD-modified PEG–PAMAM–DOX conjugates: In vitro and in vivo studies for glioma

✍ Scribed by Lihong Zhang; Saijie Zhu; Lili Qian; Yuanying Pei; Yongming Qiu; Yanyan Jiang


Book ID
116438480
Publisher
Elsevier Science
Year
2011
Tongue
French
Weight
713 KB
Volume
79
Category
Article
ISSN
0939-6411

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## Abstract In the current study, we evaluated the efficiency of folate‐polyamidoamine dendrimers conjugates (FA‐PAMAM) for the __in situ__ delivery of therapeutic antisense oligonucleotides (ASODN) that could inhibit the growth of C6 glioma cells. Folic acid was coupled to the surface amino groups