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Targeted delivery of RGD-modified liposomes encapsulating both combretastatin A-4 and doxorubicin for tumor therapy: In vitro and in vivo studies

โœ Scribed by Yi-fei Zhang; Jian-cheng Wang; Dong-yan Bian; Xuan Zhang; Qiang Zhang


Book ID
116438273
Publisher
Elsevier Science
Year
2010
Tongue
French
Weight
920 KB
Volume
74
Category
Article
ISSN
0939-6411

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Passive targeting by sterically stabilized liposomes (SSL), once combined with efficient intracellular delivery, may be a very useful strategy to improve the antitumor efficacy for the anticancer agents. The arginine-glycine-aspartic acid tripeptide (RGD) is known to serve as a recognition motif for