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RGD-CAP (βig-h3) enhances the spreading of chondrocytes and fibroblasts via integrin α1β1

✍ Scribed by Shigeru Ohno; Mitsuhide Noshiro; Seicho Makihira; Takeshi Kawamoto; Ming Shen; Weiqun Yan; Yoshie Kawashima-Ohya; Katsumi Fujimoto; Kazuo Tanne; Yukio Kato


Book ID
117351184
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
399 KB
Volume
1451
Category
Article
ISSN
0167-4889

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## Abstract βig‐h3 is an extracellular matrix (ECM) protein whose expression is highly induced by transforming growth factor beta1 (TGF‐β1). We previously demonstrated that βig‐h3 has two α3β1 integrin‐interacting motifs, which promote adhesion, migration, and proliferation of human keratinocytes.