BACKGROUND. Mepartricin, a semisynthetic polyene derivative with a favorable effect on urethro-prostatic function, was clinically evaluated, adopting the diagnostic and research criteria recommended by the First International Consultation on BPH. METHODS. A multicenter, randomized, double-blind, par
Review of recent placebo-controlled trials utilizing phytotherapeutic agents for treatment of BPH
β Scribed by Lowe, Franklin C.; Dreikorn, Kurt; Borkowski, A.; Braeckman, J.; Denis, L.; Ferrari, P.; Gerber, G.; Levin, R.; Perrin, P.; Senge, T.
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 195 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0270-4137
No coin nor oath required. For personal study only.
β¦ Synopsis
BACKGROUND.
In order to assess the efficacy of phytotherapeutic agents for the treatment of benign prostatic hyperplasia (BPH), a review of recently published double-blind placebocontrolled trials was undertaken. METHODS. Only those studies reviewed by the Other Medical Therapies Committee of the Fourth International Consultation on BPH were included. RESULTS. These studies suggest a possible benefit for the use of phytotherapeutic preparations in the treatment of BPH. CONCLUSIONS. These studies need to be confirmed in larger long-term placebo-controlled studies in order to ascertain the true efficacy of these agents.
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Interventions: Subjects were randomized to receive either 0.6 mg (0.5 mL)IM atropine or normal saline placebo in a doubleblinded manner. If pain relief with the initial injection was inadequate, patients received the alternate injection. Pain was assessed by visual analog scale (0 to 100 mm) before