Review of interactive carrier gases including ammonia in gas liquid chromatography

✍ Scribed by Mohamed Abdel-Rehim

• Publisher: John Wiley and Sons
• Year: 1999
• Tongue: English
• Weight: 127 KB
• Volume: 11
• Category: Article
• ISSN: 1040-7685
• DOI: 10.1002/(sici)1520-667x(1999)11:1<63::aid-mcs8>3.0.co;2-x

✦ Synopsis

The use of interactive carrier gases can create new possibilities for gas chromatography. In this review the possibility of utilising the ammonia and other active compounds is discussed. The influence of ammonia as carrier gas on separation and detection performance in capillary gas chromatography is discussed. Ammonia as the mobile phase resulted in improved peak symmetry, reduced retention factors and improved detection limits for aliphatic amines compared to nitrogen. Drastic selectivity changes towards some chlorophenol pairs were observed when ammonia was used as the mobile phase instead of nitrogen or helium.

Ž . Ž The selectivity of the chiral stationary phase XE-60-L-Val-S -a-PEA polysiloxane-Ž . . L-valine-S -a-phenylethylamide was drastically changed after it was exposed to ammonia for one week. The effect of ammonia on the chromatographic performance was more pronounced at lower column temperature. The presence of 50% ammonia in the carrier gas was usually enough for maximum effect on the peak symmetry and a good effect on the column selectivity. Ammonia either as a carrier gas or as a mixture in the make-up gas improved the responses of the FID, NPD and ECD.