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Review article: the potential of combinational regimen with non-steroidal anti-inflammatory drugs in the chemoprevention of colorectal cancer

โœ Scribed by M. Jalving; J. J. Koornstra; S. de Jong; E. G. E. de Vries; J. H. Kleibeuker


Book ID
108603961
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
301 KB
Volume
21
Category
Article
ISSN
0269-2813

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Distal bowel selectivity in the chemopre
โœ Hemant K. Roy; William J. Karolski; Anne Ratashak ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 225 KB

Use of non-steroidal anti-inflammatory drugs (NSAIDs) for chemoprevention of colon cancer has been hindered by their potential gastro-intestinal toxicity. Nabumetone, which is approximately 10 to 36 times safer than conventional NSAIDs, was evaluated in 2 models of experimental colon carcinogenesis.