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Chemopreventive Effects of Non-steroidal Anti-inflammatory Drugs in Early Neoplasm of Experimental Colorectal Cancer: an Apoptosome Study

✍ Scribed by Vivek Vaish; Lalita Tanwar; Jasmeet Kaur; Sankar Nath Sanyal


Book ID
107574776
Publisher
Springer US
Year
2010
Tongue
English
Weight
627 KB
Volume
42
Category
Article
ISSN
1941-6628

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✍ Hemant K. Roy; William J. Karolski; Anne Ratashak πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 French βš– 225 KB

Use of non-steroidal anti-inflammatory drugs (NSAIDs) for chemoprevention of colon cancer has been hindered by their potential gastro-intestinal toxicity. Nabumetone, which is approximately 10 to 36 times safer than conventional NSAIDs, was evaluated in 2 models of experimental colon carcinogenesis.