Reversible chorea in primary antiphospholipid syndrome
✍ Scribed by Jonas Sundén-Cullberg; Joakim Tedroff; Prof. Sten-Magnus Aquilonius
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 335 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0885-3185
No coin nor oath required. For personal study only.
✦ Synopsis
A 20-year-old woman with acute chorea induced by primary antiphospholipid syndrome was studied by using fluorodeoxyglucose and positron emission tomography (PET). PET sessions were conducted during an episode of severe chorea and after recovery. The symptoms predominantly affected the right side of her face and body, and PET demonstrated a corresponding increase in lentiform and caudate nucleus metabolism prevailing on the left side. After recovery, PET showed normal values in the regions previously studied. This study adds further evidence to support the theory that acute choreas are somehow the result of striatal hypermetabolism.
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We report the case of a patient with the unusual combination of migraine, chorea, and retinal arterial thrombosis along with laboratory evidence of autoimmunity. In the absence of systemic lupus erythematosus, the clinical manifestations suggest the presence of the primary antiphospholipid antibody
## Abstract A fourteen‐year‐old right‐handed male with a history of attention deficit hyperactivity disorder (ADHD) presented with alternating hemichorea. Laboratory findings included elevated anticardiolipin IgG and anti‐β~2~‐glycoprotein I IgG, which were consistent with primary antiphospholipid