✦ LIBER ✦

Clinical and positron emission tomography findings of chorea associated with primary antiphospholipid antibody syndrome

✍ Scribed by Steve W. Wu; Brent Graham; Michael J. Gelfand; Ralph E. Gruppo; Argirios Dinopolous; Donald L. Gilbert

Publisher: John Wiley and Sons
Year: 2007
Tongue: English
Weight: 61 KB
Volume: 22
Category: Article
ISSN: 0885-3185
DOI: 10.1002/mds.21657

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✦ Synopsis

Abstract

A fourteen‐year‐old right‐handed male with a history of attention deficit hyperactivity disorder (ADHD) presented with alternating hemichorea. Laboratory findings included elevated anticardiolipin IgG and anti‐β~2~‐glycoprotein I IgG, which were consistent with primary antiphospholipid antibody syndrome. Positron emission tomography (PET) imaging revealed altered striatal metabolism in his left putamen while he was exhibiting right‐sided hemichorea. His symptoms resolved on prednisone; however, his antiphospholipid antibody profile remained markedly abnormal despite being symptom‐free for 26 months. © 2007 Movement Disorder Society

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