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Reversed-phase high-performance liquid chromatographic determination of taxol in mouse plasma

โœ Scribed by Amarnath Sharma; Walter D. Conway; Robert M. Straubinger


Publisher
Elsevier Science
Year
1994
Weight
413 KB
Volume
655
Category
Article
ISSN
0378-4347

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## Abstract A sensitive and selective reversedโ€phase highโ€performance liquid chromatographic (HPLC) assay has been developed and validated for quantification of total topotecan in human and mouse plasma and in mouse tissue samples. Isocratic separation was achieved on a Zorbax SBโ€C~18~ column and t