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High-performance liquid chromatographic procedure for the quantitative determination of paclitaxel (Taxol®) in human plasma

✍ Scribed by Tracy A. Willey; Evan J. Bekos; Robert C. Gaver; Glenn F. Duncan; Lee K. Tay; Jos H. Beijnen; Raymond H. Farmen

Publisher
Elsevier Science
Year
1993
Weight
416 KB
Volume
621
Category
Article
ISSN
0378-4347

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High-performance liquid chromatography tandem mass spectrometry procedure with automated solid phase extraction sample preparation for the quantitative determination of paclitaxel (Taxol®) in human plasma
✍ Cristina Sottani; Claudio Minoia; Maurizio D'Incalci; Massimiliano Paganini; Mas 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 88 KB 👁 3 views

A sensitive, specific, accurate and reproducible analytical method was developed and validated for the quantitation of the anticancer agent paclitaxel in human plasma. This procedure is based on high performance liquid chromatography/ion spray -tandem mass spectrometry. This methodology is highly sp