Reversed phase chromatographic resolution of amino acid enantiomers with metal-Aspartam eluants
β Scribed by Gilon, C.; Leshem, R.; Tapuhi, Y.; Grushka, Eli
- Book ID
- 126209781
- Publisher
- American Chemical Society
- Year
- 1979
- Tongue
- English
- Weight
- 269 KB
- Volume
- 101
- Category
- Article
- ISSN
- 0002-7863
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π SIMILAR VOLUMES
A novel method for reversed-phase high-performance liquid chromatographic resolution of amino acid enantiomers by the formation of diastereomers using 8 new chiral reagent, 2,3,4,6-tetra-O-acetyl+D-glucopyranosyl isothiocyanate (GITC), is described. GITC reacts readily with enantiomeric amino acids
The enantiomers of N-(3,5\_dinitrobenzoyl)-a-amino acids are readily separated by reversed-phase chromatography on chiral stationary phases. Lipophilic interactions are quite important and largely determine the relative contributions of two competing "opposite sense" chiral recognition processes. Se