Reverse transformation of hepatic myofibroblast-like cells by TGFβ1/LAP
✍ Scribed by Masato Isono; Mariko Soda; Asuka Inoue; Hideo Akiyoshi; Kenzo Sato
- Book ID
- 116287397
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 319 KB
- Volume
- 311
- Category
- Article
- ISSN
- 0006-291X
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## Abstract ## Background/aims Transforming growth factor β (TGFβ1) is considered the key mediator in the process of liver fibrosis. The purpose of this investigation was to evaluate the activity of ribozymes against TGFβ1 in a cell‐free system and activated hepatic stellate cells (HSCs), and anti