Reverse transcriptase mutations in seque
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A. D. Gurusinghe; S. A. Land; C. Birch; C. McGavin; D. J. Hooker; G. Tachedjian;
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Article
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1995
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John Wiley and Sons
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English
β 651 KB
## Abstract Sequential human immunodeficiency virus type 1 (HIVβ1) isolates were obtained over a 29βmonth period from a person before, during, and after AZT therapy. DNA sequence analysis of polymerase chainβamplified reverseβtranscriptase gene showed a gradual accumulation of mutations to peak res