A molecular cytogenetic method consisting of chromosome microdissection and subsequent reverse/forward chromosome painting is a powerful tool to identify chromosome abnormalities of unknown origin. We present 4 cases of chromosome structural abnormalities whose origins were ascertained by this metho
Reverse painting highlights the origin of chromosome aberrations
โ Scribed by Elisabeth Blennow>
- Book ID
- 111576876
- Publisher
- Springer
- Year
- 2004
- Tongue
- English
- Weight
- 208 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0967-3849
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Background: Chromosome banding techniques and in situ hybridization reveal the majority of chromosomal aberrations. However, difficulties remain in cases of highly contracted chromosomes, poor quality of the metaphases or the presence of markers with the involvement of several chromosomes. Here, it