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Reverse Mannich reaction of some 5-hydroxyindoles

โœ Scribed by Monti, Stephen A.; Castillo, Gabriel D.


Book ID
120191281
Publisher
American Chemical Society
Year
1970
Tongue
English
Weight
529 KB
Volume
35
Category
Article
ISSN
0022-3263

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๐Ÿ“œ SIMILAR VOLUMES


Reverse Mannich reaction of some 5-hydro
โœ Monti, Stephen A.; Castillo, Gabriel D. ๐Ÿ“‚ Article ๐Ÿ“… 1970 ๐Ÿ› American Chemical Society ๐ŸŒ English โš– 529 KB

The C4-dimethylaminomethyl Mannich adducts of 3-substituted 5-hydroxyindoles undergo a facile, amine catalyzed carbon-carbon bond cleavage to yield the corresponding Ca-hydrogen indole derivatives. Reverse Mannich condensation occurs most readily in Cs-carbethoxy substrates, then in &ethyl derivativ

The mannich reaction of hydroxyindoles
โœ S.A. Monti; Wayne O. Johnson; David H. White ๐Ÿ“‚ Article ๐Ÿ“… 1966 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 226 KB

The introduction of an aminomethyl substituent into aa indole nucleus by means of a Mannich condensation is well documented. 3 In