Reverse Cope eliminations. Pyrrolidine and piperidine N-oxides by intramolecular addition of N,N-disubstituted hydroxylamines to unactivated double bonds
β Scribed by Ciganek, Engelbert
- Book ID
- 125416677
- Publisher
- American Chemical Society
- Year
- 1990
- Tongue
- English
- Weight
- 370 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
I) and addition of nitrones (II) results in a smooth condensation to give the unsaturated hydroxylamines (III) stereoselectively. These undergo reverse-Cope cyclizations at room temperature leading to the diastereomeric mixture of pyrrolidine-N-oxides (IV) and (V). -
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