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Reversal of stereochemistry by adding Ti(OiPr)4 in the enantioselective phenylacetylene addition to aldehydes using l-prolinol-backbone ligand

โœ Scribed by Jincheng Mao; Boshun Wan; Fan Wu; Rongliang Wang; Shiwei Lu


Book ID
108211471
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
93 KB
Volume
232
Category
Article
ISSN
1381-1169

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A change in the backbone substituent from phenyl to butyl group in L-serine-derived ligands provides a simple way to prepare enantiomefic products in diethylzinc addition to aldehydes.