Metabolism of FK506, a 23 member macrolide under clinical investigation as immunosuppressant after transplantation, was studied using human liver microsomes. Two fractions isolated by semipreparative HPLC were identified by negative fast atom bombardment mass spectrometry as FK506 metabolites with m
β¦ LIBER β¦
Reversal of multidrug resistance by an immunosuppressive agent FK-506
β Scribed by Mikihiko Naito; Tomoko Oh-hara; Akiko Yamazaki; Tomie Danki; Takashi Tsuruo
- Book ID
- 104887150
- Publisher
- Springer
- Year
- 1992
- Tongue
- English
- Weight
- 779 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0344-5704
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