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Reversal of drug resistance in multidrug-resistant human lung cancer cells by MRP antisense RNA mediated by retrovirus

โœ Scribed by Zhenqiang Gao; Zhiping Gao; Xifu Liu

Publisher
Springer
Year
1997
Tongue
English
Weight
447 KB
Volume
42
Category
Article
ISSN
1001-6538

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## We previously isolated agosterol A (AG -A) from a marine Spongia sp. and found that it completely reversed colchicine resistance in P-glycoprotein (Pgp)-over-expressing KB-C2 cells and vincristine resistance in multidrug-resistance protein (MRP)1-over-expressing CV60 cells. However, a tri-deacet