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Reversal of a mitochondrial DNA defect in human skeletal muscle

✍ Scribed by Clark, Kim M.; Bindoff, Laurence A.; Lightowlers, Robert N.; Andrews, Richard M.; Griffiths, Philip G.; Johnson, Margaret A.; Brierley, Elizabeth J.; Turnbull, Douglass M.

Book ID
109916519
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
412 KB
Volume
16
Category
Article
ISSN
1061-4036

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## Communicated by Henrik Dahl Seven mtDNA mutations (five base substitutions and two deletions) were studied in skeletal muscle samples of 18 human subjects aged 1 hr to 90 years. Quantitative PCR procedures were applied to determine the incidence (frequency of occurrence) and abundance (percentag