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Reveral of multidrug resistance in lung adenocarcinoma-resistant cell line A549/R by anti-sense strategy

✍ Scribed by Chen, L; Liu, Y


Book ID
118570248
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
223 KB
Volume
29
Category
Article
ISSN
0169-5002

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## Small -cell-lung-cancer (SCLC) is characterized by rapid development of resistance to cytotoxic agents, such as cisplatin (cDDP) and anthracyclines. c-myc over-expression is one of the reported genetic alterations in this tumor. Amplification of the c-myc gene in this and other cancers is often