Combination of cyclosporin A and buthionine sulfoximine (BSO) as a pharmacological strategy for circumvention of multidrug resistance in small cell lung cancer cell lines selected for resistance to doxorubicin

A study of cross-resistance pattern and

A study of cross-resistance pattern and expression of molecular markers of multidrug resistance in a human small-cell lung-cancer cell line selected with doxorubicin

✍ Rosanna Supino; Monica Binaschi; Giovanni Capranico; Romolo A. Gambetta; Elena S 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 French ⚖ 920 KB

## Abstract A doxorubicin‐resistant variant of the human small‐cell lung‐cancer cell line N592 was selected by __in vitro__ continuous exposure to increasing drug concentrations. The aim of this study was to examine the cross‐resistance pattern, cellular pharmacokinetics of doxorubicin and expressi

Differential growth inhibition and enhan

Differential growth inhibition and enhancement of major histocompatibility complex class I antigen expression by interferons in a small-cell lung cancer cell line and its doxorubicin-selected multidrug-resistant variant

✍ S. P. C. Cole; B. M. T. Campigotto; J. G. Johnson; B. E. Elliott 📂 Article 📅 1991 🏛 Springer-Verlag 🌐 English ⚖ 626 KB

Differential growth inhibition and enhan

Differential growth inhibition and enhancement of major histocompatibility complex class I antigen expression by interferons in a small-cell lung cancer cell line and its doxorubicin-selected multidrug-resistant variant

📂 Article 📅 1991 🏛 Elsevier Science 🌐 English ⚖ 152 KB

Non-P-glycoprotein-mediated multidrug re

Non-P-glycoprotein-mediated multidrug resistance in a small cell lung cancer cell line: Evidence for decreased susceptibility to drug-induced DNA damage and reduced levels of topoisomerase II

📂 Article 📅 1992 🏛 Elsevier Science 🌐 English ⚖ 168 KB

PD-147 A phase I study of a second gener

PD-147 A phase I study of a second generation antisenseoligonucleotide to clusterin (OGX-011) in combination with gemcitabine and cisplatin as first-line treatment for patients with advanced non-small cell lung cancer (NSCLC): Preliminary results

✍ Laskin, J.; Chi, K.; Melosky, B.; Sill, K.; Hao, D.; Canil, C.; Gleave, M.; Murr 📂 Article 📅 2005 🏛 Elsevier Science 🌐 English ⚖ 129 KB

Amplification of the gene for a novel mu

Amplification of the gene for a novel multidrug resistance associated protein (MRP) in non-p-glycoprotein mediated doxorubicin-selected solid tumor cells lines: M.L. Slovak, J. Ho, E.U. Kurz, R.G. Deeley and S.P.C. Cole, City of Hope National Medical Center, Duarte, CA and Cancer Research Laboratories, Queen's University Kingston, Ontario, Canada

📂 Article 📅 1993 🏛 Elsevier Science 🌐 English ⚖ 111 KB