𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Retroviral vectors for persistent expression in vivo

✍ Scribed by Robert K. Naviaux; Inder M. Verma


Book ID
113404881
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
137 KB
Volume
2
Category
Article
ISSN
0960-9822

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Retroviral vectors for persistent expres
✍ Robert K. Naviaux; Inder M. Verma πŸ“‚ Article πŸ“… 1992 πŸ› Elsevier Science 🌐 English βš– 758 KB

Retroviral vectors provide a safe and efficient method of introducing genes of therapeutic interest into dividing cells. The principle limitation of these vectors in the past has been poor gene expression in vivo. This problem has been overcome recently through the use of tissue-specific enhancers i

Encapsulated cells producing retroviral
✍ Robert M. Saller; Stefano Indraccolo; Vincenzo Coppola; Giovanni Esposito; Jan S πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 437 KB

## Abstract ## Background Because gene therapy of the future will primarily take an __in vivo__ approach, a number of problems associated with its current implementation exist. Currently, repeated delivery of a vector __in vivo__ is necessary to ensure adequate transfer of the therapeutic gene. Th

Genetic reshuffling reconstitutes functi
✍ Walter Tabotta; Dieter Klein; Christine Hohenadl; Brian Salmons; Walter H. GΓΌnzb πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 340 KB

## Background: A major prerequisite for the design of retroviral vectors encoding cell toxic or harmful genes is the possibility to tightly control gene expression, thus limiting activity to the relevant target cells and protecting the packaging cell used for production of recombinant viral particl