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Retroviral vector-mediated gene transfer into umbilical cord blood-derived megakaryocyte and platelet progenitors

โœ Scribed by Sharon M Castellino; Joanne Kurtzberg; Clay Smith


Book ID
117816133
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
242 KB
Volume
5
Category
Article
ISSN
1083-8791

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Retroviral gene transfer into cord blood
โœ Asch, Julie; Weinberg, Rona S.; Mueller, Lisa; Galperin, Yelena; Kiang, Lily; Jo ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 330 KB ๐Ÿ‘ 2 views

Cord blood (CB) progenitor/stem cells (P/SC) are ideal targets for early gene therapy in individuals prenatally diagnosed with genetic disorders. Most retroviral transduction protocols were developed using adult peripheral blood stem cells (PBSC) and bone marrow (BM). Less is known about retroviral