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Retroviral vector-mediated gene transfer into umbilical cord blood CD34brCD38−CD33− cells

✍ Scribed by Tracy Gentry; Clay Smith


Book ID
114217389
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
638 KB
Volume
27
Category
Article
ISSN
0301-472X

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Retroviral gene transfer into cord blood
✍ Asch, Julie; Weinberg, Rona S.; Mueller, Lisa; Galperin, Yelena; Kiang, Lily; Jo 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 330 KB 👁 2 views

Cord blood (CB) progenitor/stem cells (P/SC) are ideal targets for early gene therapy in individuals prenatally diagnosed with genetic disorders. Most retroviral transduction protocols were developed using adult peripheral blood stem cells (PBSC) and bone marrow (BM). Less is known about retroviral