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Retrospective review: re-treatment of patients with ovarian cancer with carboplatin after platinum resistance

โœ Scribed by H.T. See; R.S. Freedman; A.P. Kudelka; T.W. Burke; D.M. Gershenson; S. Tangjitgamol; J.J. Kavanagh

Book ID
109085422
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
89 KB
Volume
15
Category
Article
ISSN
1048-891X

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## Abstract ## BACKGROUND: Aberrant DNA methylation is a hallmark of cancer, and DNA methyltransferase inhibitors have demonstrated clinical efficacy in hematologic malignancies. On the basis of preclinical studies indicating that hypomethylating agents can reverse platinum resistance in ovarian c