Retro-Ene Reaction. Part 6. Functionalization of 4,5-Dihalopyridazin-6-ones Using 1-Acetyloxymethyl-4,5-dihalopyridazin-6-ones as the 1-O, 3-N, 5-O Ene-Adduct. -The synthesis and storage of the known 1-hydroxymethyl derivative of (I) is difficult. Thus, the functionalization of 4,5-dihalopyridazin-
Retro-Ene reaction. VI. Functionalization of 4,5-dihalopyridazin-6-ones using 1-acetyloxymethyl-4,5-dihalopyridazin-6-ones as the 1-O, 3-N, 5-O ene-adduct
✍ Scribed by Hyun-A Chung; Young-Jin Kang; Deok-Heon Kweon; Yong-Jin Yoon
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1999
- Tongue
- English
- Weight
- 602 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0022-152X
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✦ Synopsis
Abstract
Functionalization of 1‐acetyloxymethyl‐4,5‐dihalopyridazin‐6‐ones via retro‐ene reaction with some nucleophiles gave regioselectively only 5‐halo‐4‐substitutedpyridazin‐6‐ones.
📜 SIMILAR VOLUMES
Retro-Ene Reaction. Part 5. Functionalization of 4,5-Dihalopyridazin-6-ones Using 1-Hydroxymethyl-4,5-dihalopyridazin-6-ones as 1-O, 3-N, 5-O Ene Adducts. -Functionalization of title compounds (I) via a retro-ene reaction with some nucleophiles affords exclusively 4-halo substituted products such
## Abstract Functionalization of 1‐hydroxymethyl‐4,5‐dihalopyridazin‐6‐ones __via__ a retro‐ene reaction with some nucleophiles gave regioselectively only 5‐halo‐4‐substitutedpyridazin‐6‐ones.
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