✦ LIBER ✦

ChemInform Abstract: Retro-Ene Reaction. Part 5. Functionalization of 4,5-Dihalopyridazin-6-ones Using 1-Hydroxymethyl-4,5-dihalopyridazin-6-ones as 1-O, 3-N, 5-O Ene Adducts.

✍ Scribed by Hyun-A Chung; Young-Jin Kang; Joo-Wha Chung; Su-Dong Cho; Yong-Jin Yoon

Publisher: John Wiley and Sons
Year: 2010
Weight: 36 KB
Volume: 30
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199931190

No coin nor oath required. For personal study only.

✦ Synopsis

Retro-Ene Reaction.

Part 5. Functionalization of 4,5-Dihalopyridazin-6-ones Using 1-Hydroxymethyl-4,5-dihalopyridazin-6-ones as 1-O, 3-N, 5-O Ene Adducts.

-Functionalization of title compounds (I) via a retro-ene reaction with some nucleophiles affords exclusively 4-halo substituted products such as (III) or 4-halo substituted compounds as main products, cf. (I)→VIII + (IX). On the other hand, reaction of (I) with mercaptopyrimidine (X) affords the disubstituted products (XI) predominantly. Compounds (I) may be regarded to satisfy the preconditions for functionalization.

📜 SIMILAR VOLUMES

ChemInform Abstract: Retro-Ene Reaction.

ChemInform Abstract: Retro-Ene Reaction. Part 6. Functionalization of 4,5-Dihalopyridazin-6-ones Using 1-Acetyloxymethyl-4,5-dihalopyridazin-6-ones as the 1-O, 3-N, 5-O Ene-Adduct.

✍ Hyun-A Chung; Young-Jin Kang; Deok-Heon Kweon; Yong-Jin Yoon 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 34 KB 👁 2 views

Retro-Ene Reaction. Part 6. Functionalization of 4,5-Dihalopyridazin-6-ones Using 1-Acetyloxymethyl-4,5-dihalopyridazin-6-ones as the 1-O, 3-N, 5-O Ene-Adduct. -The synthesis and storage of the known 1-hydroxymethyl derivative of (I) is difficult. Thus, the functionalization of 4,5-dihalopyridazin-

ChemInform Abstract: Functionalization o

ChemInform Abstract: Functionalization of 4,5-Dihalopyridazin-6-ones Using 1-(1,1-Dibromo-2-oxopropyl) Derivatives.

✍ Y.-J. KANG; H.-A. CHUNG; D.-H. KWEON; S.-D. CHO; G.-S. LEE; S.-K KIM; Y.-J. YOON 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 35 KB

ChemInform Abstract: Retro-Ene Reactions

ChemInform Abstract: Retro-Ene Reactions. Part 4. Alkylation of 4,5-Dichloro-1-hydroxymethylpyridazin-6-one with α,ω-Dibromoalkanes or 4,5-Dichloro-1-(ω-bromoalkyl)pyridazin-6-ones.

✍ S.-K. KIM; S.-D. CHO; Y.-J. YOON 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 35 KB 👁 2 views

ChemInform Abstract: Retro-Ene Reactions

ChemInform Abstract: Retro-Ene Reactions in Heterocyclic Synthesis. Part 3. A New Route to 4,5-Dihydrooxazoles and 5,6-Dihydro-4H-1,3-oxazines.

✍ K. ITO; S. MIYAJIMA 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB 👁 2 views

ChemInform Abstract: Retro-Ene Reactions

ChemInform Abstract: Retro-Ene Reactions in Heterocyclic Synthesis. Part 4. A New Synthetic Method for 6-Hydroxypyrimidin-4(3H)-ones and 1,3,5-Triazine-2,4(1H,3H)-diones.

✍ Kunio Ito; Shingo Miyajima 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 30 KB 👁 2 views

Retro-Ene Reactions in Heterocyclic Synthesis. Part 4. A New Synthetic Method for 6-Hydroxypyrimidin-4(3H)-ones and 1,3,5-Triazine-2,4(1H,3H)-diones. -Reaction of benzamidines (I) with substituted malonates (II) and imidodicarboxylate (IV) provides an efficient access to 6-hydroxypyrimidinones (III

ChemInform Abstract: Photochemical React

ChemInform Abstract: Photochemical Reactions of 1-Methoxymethylbicyclo[4.3.0]non-6-en-8-one and 5 Methoxymethylbicyclo[3.3.0]oct-1-en-3-one.

✍ Ann-Kuo Lai; Chein-Dhau Lee; Chun-Chen Liao 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 29 KB 👁 1 views