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Retinopathy is associated with higher glycaemia in maturity-onset type diabetes

✍ Scribed by J. Howard-Williams; R. M. Hillson; A. Bron; P. Awdry; J. I. Mann; T. D. R. Hockaday


Publisher
Springer
Year
1984
Tongue
English
Weight
574 KB
Volume
27
Category
Article
ISSN
0012-186X

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✦ Synopsis


In a group of 149 maturity-onset type diabetic patients followed from diagnosis, 55 (37%) had retinopathy on colour photography 7 years later. Those patients with retinopathy had significantly greater glycaemia, as shown by higher fasting plasma glucose levels at diagnosis, larger mean values for fasting glucose 1, 3 and 5 years later, and higher random glucose and haemoglobin A1c at ophthalmic review (p = 0.001, 0.002, 0.007 and 0.001, respectively). Substantial retinopathy, as measured by greater than 5 microaneurysms, also correlated significantly with each index of glycaemic control.


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## Abstract Three non‐insulin‐dependent (Type 2) diabetic patients were assessed for the presence of significant and progressive retinopathy within 12 months of diagnosis. All subjects required specialist referal for fluorescein angiography but retinal abnormalities regressed within two‐to‐six mont