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Retinoids, Retinoic Acid Receptors, and Cancer

✍ Scribed by Tang, Xiao-Han; Gudas, Lorraine J.

Book ID
115497324
Publisher
Annual Reviews
Year
2011
Tongue
English
Weight
598 KB
Volume
6
Category
Article
ISSN
1553-4006

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## Abstract The biological effects of retinoic acid (RA) are mediated by nuclear retinoic acid receptors (RARs) that function as ligand‐activated transcriptional factors. The response of human cancer cells to RA is known to be associated with the expression of RARΞ². Recent studies have demonstrated