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Retinoic acid suppresses endothelin-1 gene expression at the transcription level in endothelial cells

✍ Scribed by Jinko Yokota; Masatoshi Kawana; Chiaki Hidai; Yoshikazu Aoka; Ken-ichiro Ichikawa; Nobuo Iguchi; Masako Okada; Hiroshi Kasanuki

Book ID
119435315
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
194 KB
Volume
159
Category
Article
ISSN
0021-9150

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Arachidonic acid induces endothelin-1 ge
Arachidonic acid induces endothelin-1 gene expression in vascular endothelial cells
✍ Maria Teresa Rizzo; Wen-mei Yu πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 176 KB πŸ‘ 1 views

Endothelin-1 (ET-1) is a potent vasoconstrictor peptide synthesized and secreted by vascular endothelial cells. Regulation of ET-1 production occurs at the level of gene transcription. We previously demonstrated a role for arachidonic acid as an intracellular mediator in the regulation of gene expre