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Retinoic acid stimulation of gelatinase A (MMP-2) and matrilysin (MMP-7) expression in human prostate epithelial cells

✍ Scribed by Michael J Wilson; Carol Wiehr; Ori Melamud; Stephen L Ewing; Duanqing Pei; Akhouri A Sinha; Donna M Peehl

Book ID
118645097
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
68 KB
Volume
2
Category
Article
ISSN
1569-9056

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## Abstract P450 aromatase catalyzes the conversion of androgens to estrogens and plays a key role in the cell growth of hormone‐dependent breast cancer in postmenopausal women. On the other hand, matrix metalloproteinases (MMPs), which can degrade almost all components of the extracellular matrix,