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Modulation of MMP-2 (gelatinase A) and MMP-9 (gelatinase B) by interferon-γ in a human salivary gland cell line

✍ Scribed by Ava J. Wu; Robert M. Lafrenie; Chan Park; Wandee Apinhasmit; Zhi Jian Chen; Henning Birkedal-Hansen; Kenneth M. Yamada; William G. Stetler-Stevenson; Bruce J. Baum


Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
237 KB
Volume
171
Category
Article
ISSN
0021-9541

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Interferon-γ-induced JAK2 and STAT1 sign
✍ Ava J. Wu; Zhi Jian Chen; Elaine C. Kan; Bruce J. Baum 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 166 KB 👁 1 views

We have used a human salivary gland cell line (HSG) as a possible in vitro model to evaluate the effects of IFN-g on human salivary gland epithelium (Wu et al., , 1996(Wu et al., , 1997)). In the present study, we examined the JAK-STAT signal-transduction pathway in IFN-g-treated HSG cells. We demon