## Abstract Erythropoietin (Epo) is known to have a significant role in tissues outside the hematopoietic system. In this work, we investigated the function of Epo in cells of neuronal origin subjected to differentiation. Treatment of SHβSY5Y cells with allβ__trans__βretinoic acid (atRA) generated
Retinoic acid receptors and tissue-transglutaminase mediate short-term effect of retinoic acid on migration and invasion of neuroblastoma SH-SY5Y cells
β Scribed by Joshi, S; Guleria, R; Pan, J; DiPette, D; Singh, U S
- Book ID
- 110070063
- Publisher
- Nature Publishing Group
- Year
- 2005
- Tongue
- English
- Weight
- 390 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0950-9232
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## Abstract Retinoic acid (RA), an active metabolite of vitamin A, is a natural morphogen involved in development and differentiation of the nervous system. To elucidate signaling mechanisms involved in RAβinduced neuritogenesis, we used human neuroblastoma SHβSY5Y cells, an established in vitro mo
## Abstract ## Background Because of the known property of less aggressiveness of differentiated cells compared to immatured cells all attempts are made to elucidate whether differentiation inducers possibly could be applied for neuroblastoma therapy. We are interested in examining the influence o