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Synergistic anti-proliferative effects of vitamin D derivatives and 9-cis retinoic acid in SH-SY5Y human neuroblastoma cells

✍ Scribed by Maria Stio; Alessandra Celli; Cristina Treves


Book ID
117668169
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
365 KB
Volume
77
Category
Article
ISSN
0960-0760

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## Abstract Abstract vitamin D receptor (VDR) and retinoid X receptor (RXR) heterodimerize to mediate the genomic actions of 1α,25‐dihydroxyvitamin D~3~ (1α,25(OH)~2~D~3~, calcitriol), the biologically active form of vitamin D~3~. In this study, we show that 9‐__cis__ retinoic acid (9‐cisRA), the l