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Retinoic-acid-induced differentiation of HL-60 cells is associated with biphasic activation of the Na+ — K+ pump

✍ Scribed by Annie Ladoux; Jean-Pierre Abita; Blandine Geny


Book ID
115111116
Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
588 KB
Volume
33
Category
Article
ISSN
0301-4681

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## Abstract During differentiation of human leukemic HL60 cells into granulocytes, sustained increases in intracellular pH and Na^+^/H^+^ antiporter activity have been observed. In the present study we report that retinoic acid (RA)‐induced granulocytic differentiation of HL60 cells causes an ∼18‐f