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Retinoic acid decreases expression of insulin-like growth factor (IFG)-II by HT-29 cells

โœ Scribed by Mark R. Corkins; Beverly S. Schaffer; Richard G. MacDonald


Book ID
119424209
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
175 KB
Volume
118
Category
Article
ISSN
0016-5085

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Down-regulation of insulin-like growth f
โœ Dae-Ghon Kim; Dae-yeol Lee; Baik-Hwan Cho; Kyung-Ran You; Mi-Young Kim; Deuk-Soo ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 237 KB ๐Ÿ‘ 1 views

We observed that all-trans-retinoic acid (RA) down-regulated insulin-like growth factor binding proteins (IGFBPs) in cultured human hepatoma cells (Hep 3B, PLC/PRF/5, and Hep G2); therefore, we characterized the role of this down-regulation in cell growth. Treatment with 10 micromol/L RA revealed a