Retinoblastoma (RB) is an important ocular malignancy of childhood. It has been commonly accepted for some time that knockout of the two alleles of the RB1 gene is the principal molecular target associated with the occurrence of RB. In this article, we examine the validity of the two-hit theory for
Retinoblastoma: Revisiting the model prototype of inherited cancer
β Scribed by Lohmann, Dietmar R. ;Gallie, Brenda L.
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 80 KB
- Volume
- 129C
- Category
- Article
- ISSN
- 0148-7299
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