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Retention of Ionizable Compounds in Reversed-Phase Liquid Chromatography. Effect of the Ionic Strength of the Mobile Phase and the Nature of the Salts Used on the Overloading Behavior

✍ Scribed by Gritti, Fabrice; Guiochon, Georges


Book ID
125435662
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
167 KB
Volume
76
Category
Article
ISSN
0003-2700

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The pressure in a chromatographic system was found to have a significant effect on the retention of solutes in the ionization control mode in reversed-phase liquid chromatography. An increase in the pressure in a column by 200 kg/cm2 resulted in as much as a 12% variation in k', and caused peak reve