The anticonvulsant properties of the endogenous excitatory amino acid antagonist, kynurenic acid (KYA), were studied in prepubescent and adult rats using the amygdaloid kindling model of epilepsy. Treatment with intracerebroventricular KYA (360 nmoles (adult dose) or 240 nmoles (prepuhescent dose))
Retardation of amygdaloid kindling in the rat by the excitatory amino acid antagonist kynurenic acid
โ Scribed by Zoe Dennison; Donald P. Cain
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 365 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0887-4476
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๐ SIMILAR VOLUMES
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The actions of excitatory amino acid (EAA) antagonists on synaptic inputs to neurons in the rat medial vestibular nucleus (MVN) from ipsilateral vestibular afferents and vestibular commissures were studied in brain stem slice preparations. Antagonists used were 2-amino-5-phosphonovalerate (APV), a s
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