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RET proto-oncogene mutations are restricted to codons 634 and 918 in mainland Chinese families with MEN2A and MEN2B

✍ Scribed by Yulin Zhou; Yongju Zhao; Bin Cui; Liqun Gu; Shaoxin Zhu; Jianjun Li; Jinbo Liu; Ming Yin; Tieyun Zhao; Zhiqiang Yin; Chaoli Yu; Changyou Chen; Liming Wang; Buyun Xiao; Jie Hong; Yifei Zhang; Zhengyi Tang; Shu Wang; Xiaoying Li; Guang Ning

Book ID
108703815
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
130 KB
Volume
0
Category
Article
ISSN
0300-0664

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Diagnosis of multiple endocrine neoplasi
Diagnosis of multiple endocrine neoplasia [MEN] 2A, 2B and familial medullary thyroid cancer [FMTC] by multiplex PCR and heteroduplex analyses of RET proto-oncogene mutations
✍ Marios Kambouris; Charles E. Jackson; Gerald L. Feldman πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 1006 KB

Communicated by B w e A.J. Pondei Multiple endocrine neoplasia type 2 [MEN 21 is an autosomal dominant cancer syndrome with two subtypes, 2A and 2B. MEN 2A and medullary thyroid cancer [MTC] are caused by >25 different point mutations in exons 10, 11, and 13 of the RET proto-oncogene, whereas MEN 2B