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Resveratrol Reverses Tumor-Promoter-Induced Inhibition of Gap-Junctional Intercellular Communication

✍ Scribed by Mette Nielsen; Randall J. Ruch; Ole Vang

Book ID
115586457
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
78 KB
Volume
275
Category
Article
ISSN
0006-291X

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## Abstract The plasma‐membrane association and transforming activity of the ras oncoprotein p21 are dependent upon posttranslational farnesylation. Farneslyl synthesis and p21 ras farnesylation are inhibited by hydroxmethylglutaryl‐CoA reductase inhibitors such as lovastatin. In this study, we exa