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Resveratrol Induces Apoptosis in Thyroid Cancer Cell Lines via a MAPK- and p53-Dependent Mechanism

✍ Scribed by Shih, Ai; Davis, Faith B.; Lin, Hung-Yun; Davis, Paul J.

Book ID
121870170
Publisher
Endocrine Society
Year
2002
Tongue
English
Weight
732 KB
Volume
87
Category
Article
ISSN
0021-972X

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## Abstract Cyclooxygenase‐2 (COX‐2) content is increased in many types of tumor cells. We have investigated the mechanism by which resveratrol, a stilbene that is pro‐apoptotic in many tumor cell lines, causes apoptosis in human head and neck squamous cell carcinoma UMSCC‐22B cells by a mechanism