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PPARγ ligand-induced apoptosis through a p53-dependent mechanism in human gastric cancer cells

✍ Scribed by Miho Nagamine; Toshikatsu Okumura; Satoshi Tanno; Mitsuko Sawamukai; Wataru Motomura; Nobuhiko Takahashi; Yutaka Kongo


Book ID
108582269
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
368 KB
Volume
94
Category
Article
ISSN
1347-9032

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## BACKGROUND. Apoptosis is induced by various anticancer agents or radiation through the tumor suppressor gene p53-dependent pathway and is also induced by other factors, including transforming growth factor-PI (TGF-0,). In this study, the authors investigated whether TGF-0, would induce apoptosi